Dr. Gelareh Zadeh

BSc, MD, PhD, FRCSC, FAANS

Head, Division of Surgical Oncology, Department of Surgery, UHN

Interim Head, Department of Neurosurgery, Toronto Western Hospital, UHN 

Professor, Department of Surgery, University of Toronto

Medical Co-Director, Krembil Brain Institute

Chair, Wilkins Family Brain Tumor Research 
Co-Director, Elizabeth Raab Neurofibromatosis Program 
Director, CNS Biobanking

Bio

Her clinical practice focuses on Skull Base Neuro-oncology, with dedicated general brain tumour clinic and many multidisciplinary clinics that she has established and is actively involved with such as skull base, pituitary, brain metastases, gamma knife and neurofibromatosis clinic. She is actively involved with and is dedicated to the goal of advancing surgical clinical trials. 

Her research laboratory is focused on studying the molecular mechanisms of glioma angiogenesis and molecular regulators of tumour metabolism. Specifically investigating the role of bone marrow-derived cells in supporting tumour vasculature in gliomas and how differentiation into macrophage and microglia population plays a role in escape mechanisms of evading anti-angiogenic therapy. A second focus of the laboratory, on tumour metabolism, explores the interplay between altered metabolism in response to anti-angiogenic therapy. She also has a translational program, dedicated to establishing the genomic landscape of meningiomas and schwannomas. Her laboratory is funded through peer-reviewed grants from a number of agencies such as CIHR, Terry Fox New Investigator grant, CCSRI, CRS, BrainChild and others.

Specialty

Neuro-Oncology 

Diseases Treated

Skull base and pituitary tumours
Brain metastases  
Acoustic neuroma/schwannoma

Neurofibromatosis

Clinics 

Brain Metastasis Clinic 

Neuro-Oncology Clinic 

Pituitary Clinic 

Neurofibromatosis Clinic 

Skull Base Clinic 

Gamma Knife Clinic 

Languages 

English

Farsi

Contact Information 

Phone: 416 603 5679
Fax: 416 603 5298
Email: gelareh.zadeh@uhn.ca

Education and Training  

MD, University of Manitoba, Canada, 1996, 
BSc(Med), University of Manitoba, Canada, 1996, Medical Research 
FRCSC, Division of Neurosurgery, University of Toronto, 1996-2006, Medical Research 
PhD, Institute of Medical Science, University of Toronto, 1999-2006, Molecular Biology 
Fellowship, University College London, UK Cancer Care Ontario Funding, 2006-2007

Academic Affiliations 

Professor, Department of Surgery, University of Toronto (Neurosurgery)

Director, Academic Affairs, Division of Neurosurgery, University of Toronto

Research Affiliations 

Scientist, Ontario Research Institute 
Scientist, Labatt's Brain Tumor Research Institute 
Scientist, MacFeeters-Hamilton Program, Ontario Cancer Institute 
Adjunct Scientist, Hospital for Sick Children 
Krembil Research Institute 
Visit Dr. Zadeh's website at: www.zadehlab.com

UHN Research Profile

http://www.uhnresearch.ca/researchers/profile.php?lookup=6839

PubMed Link

http://www.ncbi.nlm.nih.gov

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